Welcome to the Duke Human Vaccine Institute

The School of Medicine’s Dean Mary Klotman, MD, commemorated World AIDS Day (December 1) in conversation with our director, Barton Haynes, MD. Watch below to hear more on how he and our team of scientists are engineering the immune system to fight HIV.

The Duke Human Vaccine Institute (DHVI) continues to lead with cutting edge vaccine research against infectious diseases that impact global health.

Scientists at the DHVI conduct basic and translational research to develop novel vaccines, therapeutics, and diagnostics for diseases such as HIV-1, influenza, SARS-CoV-2, tuberculosis, syphilis, and gonorrhea. Several DHVI basic science discoveries are currently being produced in Good Manufacturing Practice (CGMP) facilities for early phase vaccine trials.

DHVI has established a place of national and international leadership in the fight against major infectious diseases. We play an integral leadership role in the Global HIV/AIDS Vaccine Enterprise and we are a pioneer in emerging infections and biodefense research.

A World AIDS Day conversation between Duke School of Medicine’s Dean Mary Klotman, MD, and Barton Haynes, MD, director of DHVI.

Join us in leading the fight against major infectious diseases!

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Listen directly from our scientists as they explain the path to creating a universal vaccine to fight future coronaviruses. 

Learn how researchers at the Duke Human Vaccine Institute lead research in vaccine development
Learn about the state-of-the-art program to prevent pandemics related to flu
An innovative approach to tackling COVID-19 on Duke's campus