Emmanuel B.Walter Jr., MD, MPH

Professor of Pediatrics


2608 Erwin Road, Suite 210
Durham, NC 27705

Department / Division

Professor of Pediatrics


M.P.H., University of North Carolina at Chapel Hill (1992)
M.D., University of Maryland, College Park (1983)
B.S., University of Notre Dame (1979)

Dr. Emmanuel Walter, MD, MPH, Professor of Pediatrics, serves as the Duke Human Vaccine Institute (DHVI) Chief Medical Officer and directs the Duke Vaccine and Trials Unit. In these roles, Dr. Walter provides strategic and operational leadership for clinical research conducted at the Institute.  In addition, he provides oversight of regulatory compliance for DHVI clinical research activities.

Dr. Walter has dedicated his career to advancing research and clinical practice in vaccinology, infectious diseases, and child health. He currently serves as the principal investigator for the Duke Clinical Core of the Collaborative Influenza Vaccine Innovations Centers (CIVICs) funded by the National Institute of Allergy and Infectious Diseases (NIAID).  The goal of this work is to evaluate promising next generation influenza vaccine candidates in Phase I and Phase I/II clinical trials and human challenge studies.  He is the Duke Co-Principal Investigator for the NIAID Vaccine and Treatment Evaluation Unit (VTEU) which conducts clinical trials of vaccines and treatments for infectious diseases.  He is also the Duke Principal Investigator for the CDC-funded Clinical Immunization Safety Assessment Project which conducts studies to identify risk factors and preventive strategies for adverse events following immunization, particularly in special populations. Lastly, he is the Principal Investigator for a CDC-funded project to further understand and reduce disparities in vaccine coverage among rural adolescents.

Dr. Walter's focused area of interest include vaccine development, vaccine safety, vaccine coverage, prevention and treatment of infectious diseases.

DVTU Website 

Representative Publications

Brady, AM; Walter, EB; Markowitz, LE; Unger, ER; Panicker, G
Bernstein, DI; Guptill, J; Naficy, A; Nachbagauer, R; Berlanda-Scorza, F; Feser, J; Wilson, PC; Solórzano, A; Van der Wielen, M; Walter, EB; Albrecht, RA; Buschle, KN; Chen, Y-Q; Claeys, C; Dickey, M; Dugan, HL; Ermler, ME; Freeman, D; Gao, M; Gast, C; Guthmiller, JJ; Hai, R; Henry, C; Lan, LY-L; McNeal, M; Palm, A-KE; Shaw, DG; Stamper, CT; Sun, W; Sutton, V; Tepora, ME; Wahid, R; Wenzel, H; Wohlbold, TJ; Innis, BL; García-Sastre, A; Palese, P; Krammer, F
Keitel, WA; Voronca, DC; Atmar, RL; Paust, S; Hill, H; Wolff, MC; Bellamy, AR; VTEU H5N1 Vaccine Working Group,
Munoz, FM; Anderson, EJ; Bernstein, DI; Harrison, CJ; Pahud, B; Anderson, E; Creech, CB; Berry, AA; Kotloff, KL; Walter, EB; Atmar, RL; Bellamy, AR; Chang, S; Keitel, WA
Hills, SL; Walter, EB; Atmar, RL; Fischer, M; ACIP Japanese Encephalitis Vaccine Work Group,
Edwards, JM; Watson, N; Focht, C; Wynn, C; Todd, CA; Walter, EB; Phillips Heine, R; Swamy, GK
Edwards, JM; Watson, N; Focht, C; Wynn, C; Todd, CA; Walter, EB; Heine, RP; Swamy, GK
Fortner, KB; Swamy, GK; Broder, KR; Jimenez-Truque, N; Zhu, Y; Moro, PL; Liang, J; Walter, EB; Heine, RP; Moody, MA; Yoder, S; Edwards, KM