Funding Opportunities

Collaborative Development Awards (CDA)

Overview

The Duke Center for HIV Structural Biology (DCHSB) invites proposals for an HIV research funding opportunity (Collaborative Development Awards - CDA). The program is intended to broadly support HIV-related structural studies aligned with the goals of the Center. Early-career HIV investigators and investigators new to HIV research from under-represented racial and ethnic groups are encouraged to apply.

Award Information

  • Proposals must include a detailed budget up to $175,000 (in total costs) based on scope of work proposed. Depending on the number of meritorious applicants and their budgets, the Review Committee will determine how many total proposals will be funded. Funds can be used to cover salary support and other research-related expenses.
  • The project plan should be accomplished within one year from date of award. Proposals should include a clear timeline and plan for completion.

Eligibility Criteria

  • Early-career HIV investigators who have completed their terminal research degree or end of post-graduate clinical training, whichever date is later, within the past 10 years, and who have not previously competed successfully as PD/PI for a substantial NIH independent research award (R01 or similar) and investigators new to HIV research are eligible to apply for the Collaborative Development Awards.
  • Applicants should not be associated with the Duke Center for HIV Structural Biology.
  • Researchers from under-represented racial and ethnic groups are encouraged to apply.
  • In the period preceding the application due date, candidates will submit an eligibility form and email it to Whitney Beck, scientific program leader, that lays out their years as an early investigator and/or new to the field, subspecialty and institution, proposed mentor and topic of research.
  • Early-career investigators are encouraged to select research mentors who are NIH-funded investigators with proven expertise in the area of research interest and in the career development of independent investigators.

Project Details

  • One of the goals of the CDA awards is to actively seek candidates who can bring additional technologies to complement the expertise of the structural biology toolbox. These will include spectroscopic techniques such as nuclear magnetic resonance (NMR) spectroscopy, single-molecule fluorescence resonance energy transfer (sm-FRET) and electron paramagnetic resonance (EPR) spectroscopy. NMR, smFRET and EPR have been used successfully to understand HIV-1 Env structure and dynamics. Projects in any area, including basic, clinical or translational, will be considered.
  • Prior to start of any research, appropriate human subjects and/or animal certifications will be required.

Application Process

Applications should contain all of the items listed below:

  • Cover Sheet
  • Personal Statement
  • Project Abstract
  • Key Personnel
  • Biographical sketches for candidate and mentor
  • Budget (not to exceed $175,000 in total costs)
  • Budget Justification
  • Facilities/Resources

Research Plan is limited to 6 pages (excluding references).

  • R21-style 6-page research plan, written by the candidate in PHS 398 format.

Application Form

Please download the application form (an editable .doc file), complete it, and save as one PDF file to be uploaded to the submission link below.

Submission Form

Open the online form to submit your application.

Review Process

  • Peer review by a panel convened by the Center’s investigators.
  • Candidate interviews will be conducted through a virtual platform with interviewers with expertise that matches the field of applicants. In two 1-on-1 interviews, Selection Committee members will evaluate key criteria for each applicant: a) quality of the research project; b) anticipated quality of career guidance and mentoring by the sponsoring department and research mentor; c) academic stature of the proposed research mentor; d) applicant’s understanding and appreciation of the relationship of the proposed research to a high-priority question in HIV biology; e) applicant’s long-term scientific goals; and f) applicant’s intellectual curiosity, thoughtfulness, perseverance, and personal academic achievement.
  • After the interviews, the Selection Committee will construct a rank list of candidates to establish priorities for funding.
  • Intent is to complete reviews and start funding by December 1, 2022.
  • To assess the progress of the funded projects, each awardee will be required to submit quarterly one-page progress reports and to present the progress of the project during the DCHSB annual meeting.

Deadline

Applications must be submitted electronically no later than September 12, 2022, 5 p.m. EST

Confidentiality

The DCHSB and the review panel will endeavor to maintain the confidentiality of all applicant intellectual property.

Project Contact

For questions regarding these proposal guidelines, eligibility requirements, review criteria, or for other information related to this award, please contact:

Whitney Edwards Beck, BS
Scientific Program Leader

Maria Blasi, PhD
Lead Developmental Core


Jason McLellan, PhD
Co-
Lead Developmental Core


Ivelin Georgiev, PhD
Co-
Lead Developmental Core