Guido Ferrari, MD

Associate Professor of Surgery
Associate Research Professor in Molecular Genetics and Microbiology
Duke University School of Medicine

Contact Info

(919) 684-2862

Location

115 Surg Oncol Res Fac
Durham, NC 27710

Department / Division

Surgery / Surgical Sciences

Training

MD, University of Genoa (Italy), 1985

Over the past eleven years, I have built an independent basic research and immune monitoring laboratory with continuous NIH and Bill & Melinda Gates Foundation funding and continue to develop productive collaboration within and outside Duke University Medical Center, allowing me to expand my focus of research. Overall, I have been interested in understanding the ontogeny of HIV-1 specific immune responses that work by eliminating HIV-1 infected cells and how these can be induced by AIDS vaccine candidates. Lately, I have also started investigating the influence of CD4+ T cell responses that may support the production of broadly neutralizing Ab following HIV-1 infection. In summary, the research in my laboratory revolves around three topics of interest: class I-mediated cytotoxic CD8+ T cell responses, antibody-dependent cellular cytotoxicity (ADCC), gene expression in T cellular subsets upon infection with HIV-1.

Representative Publications

Rountree W, Berrong M, Sanchez AM, Denny TN, Ferrari G. J Immunol Methods. 2016 Mar 25. pii: S0022-1759(16)30053-9. doi: 10.1016/j.jim.2016.03.004. [Epub ahead of print]
Pollara J, Bonsignori M, Moody MA, Liu P, Alam SM, Hwang KK, Gurley TC, Kozink DM, Armand LC, Marshall DJ, Whitesides JF, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Rerks-Ngarm S, Robb ML, O'Connell RJ, Kim JH, Michael NL, Montefiori DC, Tomaras GD, Liao HX, Haynes BF, Ferrari G. J Virol. 2014 Jul;88(14):7715-26. doi: 10.1128/JVI.00156-14. Epub 2014 May 7.
Sambor A, Garcia A, Berrong M, Pickeral J, Brown S, Rountree W, Sanchez A, Pollara J, Frahm N, Keinonen S, Kijak GH, Roederer M, Levine G, D'Souza MP, Jaimes M, Koup R, Denny T, Cox J, Ferrari G. J Immunol Methods. 2014 Jul;409:107-16. doi: 10.1016/j.jim.2014.04.005. Epub 2014 Apr 29.
Sanchez AM, Rountree W, Berrong M, Garcia A, Schuetz A, Cox J, Frahm N, Manak M, Sarzotti-Kelsoe M, D'Souza MP, Denny T, Ferrari G. J Immunol Methods. 2014 Jul;409:31-43. doi: 10.1016/j.jim.2014.03.017. Epub 2014 Mar 28.