September 01, 2020

DHVI Investigator receives NIAID R56 grant

Congratulations to Dr. Maria Blasi for receiving an NIAID R56 entitled: “Targeting the HIV-1 reservoir with a combination of an IDLV-SIVGag therapeutic vaccine and Fc-engineered bnAbs”.  Dr. Blasi and team have recently demonstrated that the IDLV-SIV-Gag therapeutic vaccine induced durable control of viremia in chronically SHIV infected macaques. The proposed research builds on those results and will determine whether the combination of the IDLV therapeutic vaccine and a cocktail of engineered bnAbs could be a strategy to induce durable virologic control and impact the size of the HIV reservoir.