Duke Human Vaccine Institute

Munir Alam, PhD

Professor in Medicine

Contact Info

(919) 668-6372
alam0004@mc.duke.edu

Location

2 Genome Ct, MSRB II - Room 4004
Durham, NC 27710

Department / Division

Professor of Pathology

Training

Ph.D., University of Glasgow (Scotland) (1992)

Representative Publications

Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies. (09/2019)
LaBranche, CC; Henderson, R; Hsu, A; Behrens, S; Chen, X; Zhou, T; Wiehe, K; Saunders, KO; Alam, SM; Bonsignori, M; Borgnia, MJ; Sattentau, QJ; Eaton, A; Greene, K; Gao, H; Liao, H-X; Williams, WB; Peacock, J; Tang, H; Perez, LG; Edwards, RJ; Kepler, TB; Korber, BT; Kwong, PD; Mascola, JR; Acharya, P; Haynes, BF; Montefiori, DC
Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. (07/2019)
Han, Q; Jones, JA; Nicely, NI; Reed, RK; Shen, X; Mansouri, K; Louder, M; Trama, AM; Alam, SM; Edwards, RJ; Bonsignori, M; Tomaras, GD; Korber, B; Montefiori, DC; Mascola, JR; Seaman, MS; Haynes, BF; Saunders, KO
Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period. (05/2019)
Spearman, P; Tomaras, GD; Montefiori, DC; Huang, Y; Elizaga, ML; Ferrari, G; Alam, SM; Isaacs, A; Ahmed, H; Hural, J; McElrath, MJ; Ouedraogo, L; Pensiero, M; Butler, C; Kalams, SA; Overton, ET; Barnett, SW; HVTN 088 Protocol Team and the NIH/NIAID HIV Vaccine Trials Network,
Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. (03/2019)
Krebs, SJ; Kwon, YD; Schramm, CA; Law, WH; Donofrio, G; Zhou, KH; Gift, S; Dussupt, V; Georgiev, IS; Schätzle, S; McDaniel, JR; Lai, Y-T; Sastry, M; Zhang, B; Jarosinski, MC; Ransier, A; Chenine, AL; Asokan, M; Bailer, RT; Bose, M; Cagigi, A; Cale, EM; Chuang, G-Y; Darko, S; Driscoll, JI; Druz, A; Gorman, J; Laboune, F; Louder, MK; McKee, K; Mendez, L; Moody, MA; O'Sullivan, AM; Owen, C; Peng, D; Rawi, R; Sanders-Buell, E; Shen, C-H; Shiakolas, AR; Stephens, T; Tsybovsky, Y; Tucker, C; Verardi, R; Wang, K; Zhou, J; Zhou, T; Georgiou, G; Alam, SM; Haynes, BF; Rolland, M; Matyas, GR; Polonis, VR; McDermott, AB; Douek, DC; Shapiro, L; Tovanabutra, S; Michael, NL; Mascola, JR; Robb, ML; Kwong, PD; Doria-Rose, NA
Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques. (03/2019)
Dennis, M; Eudailey, J; Pollara, J; McMillan, AS; Cronin, KD; Saha, PT; Curtis, AD; Hudgens, MG; Fouda, GG; Ferrari, G; Alam, M; Van Rompay, KKA; De Paris, K; Permar, S; Shen, X
Inference of the HIV-1 VRC01 Antibody Lineage Unmutated Common Ancestor Reveals Alternative Pathways to Overcome a Key Glycan Barrier. (12/2018)
Bonsignori, M; Scott, E; Wiehe, K; Easterhoff, D; Alam, SM; Hwang, K-K; Cooper, M; Xia, S-M; Zhang, R; Montefiori, DC; Henderson, R; Nie, X; Kelsoe, G; Moody, MA; Chen, X; Joyce, MG; Kwong, PD; Connors, M; Mascola, JR; McGuire, AT; Stamatatos, L; Medina-Ramírez, M; Sanders, RW; Saunders, KO; Kepler, TB; Haynes, BF
Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques. (10/2018)
Phillips, B; Van Rompay, KKA; Rodriguez-Nieves, J; Lorin, C; Koutsoukos, M; Tomai, M; Fox, CB; Eudailey, J; Dennis, M; Alam, SM; Hudgens, M; Fouda, G; Pollara, J; Moody, A; Shen, X; Ferrari, G; Permar, S; De Paris, K
Qualified Biolayer Interferometry Avidity Measurements Distinguish the Heterogeneity of Antibody Interactions with Plasmodium falciparum Circumsporozoite Protein Antigens. (08/2018)
Dennison, SM; Reichartz, M; Seaton, KE; Dutta, S; Wille-Reece, U; Hill, AVS; Ewer, KJ; Rountree, W; Sarzotti-Kelsoe, M; Ozaki, DA; Alam, SM; Tomaras, GD
Functional Relevance of Improbable Antibody Mutations for HIV Broadly Neutralizing Antibody Development. (06/2018)
Wiehe, K; Bradley, T; Meyerhoff, RR; Hart, C; Williams, WB; Easterhoff, D; Faison, WJ; Kepler, TB; Saunders, KO; Alam, SM; Bonsignori, M; Haynes, BF
HIV-1 Envelope Glycoproteins from Diverse Clades Differentiate Antibody Responses and Durability among Vaccinees. (04/2018)
Yates, NL; deCamp, AC; Korber, BT; Liao, H-X; Irene, C; Pinter, A; Peacock, J; Harris, LJ; Sawant, S; Hraber, P; Shen, X; Rerks-Ngarm, S; Pitisuttithum, P; Nitayapan, S; Berman, PW; Robb, ML; Pantaleo, G; Zolla-Pazner, S; Haynes, BF; Alam, SM; Montefiori, DC; Tomaras, GD

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