Duke Human Vaccine Institute

Munir Alam, PhD

Professor in Medicine

Contact Info

(919) 668-6372
alam0004@mc.duke.edu

Location

2 Genome Ct, MSRB II - Room 4004
Durham, NC 27710

Department / Division

Professor of Pathology

Training

Ph.D., University of Glasgow (Scotland) (1992)
Ph.D., University of Glasgow (United Kingdom) (1992)

Representative Publications

Antigenicity and Immunogenicity of HIV-1 Envelope Trimers Complexed to a Small-Molecule Viral Entry Inhibitor. (10/2020)
Alam, SM; Cronin, K; Parks, R; Anasti, K; Ding, H; Go, EP; Desaire, H; Eaton, A; Montefiori, D; Sodroski, J; Kappes, J; Haynes, BF; Saunders, KO
3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates. (06/2020)
Kasturi, SP; Rasheed, MAU; Havenar-Daughton, C; Pham, M; Legere, T; Sher, ZJ; Kovalenkov, Y; Gumber, S; Huang, JY; Gottardo, R; Fulp, W; Sato, A; Sawant, S; Stanfield-Oakley, S; Yates, N; LaBranche, C; Alam, SM; Tomaras, G; Ferrari, G; Montefiori, D; Wrammert, J; Villinger, F; Tomai, M; Vasilakos, J; Fox, CB; Reed, SG; Haynes, BF; Crotty, S; Ahmed, R; Pulendran, B
HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy. (03/2020)
Curtis, AD; Dennis, M; Eudailey, J; Walter, KL; Cronin, K; Alam, SM; Choudhary, N; Tuck, RH; Hudgens, M; Kozlowski, PA; Pollara, J; Ferrari, G; Van Rompay, KKA; Permar, S; De Paris, K
Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency. (01/2020)
Easterhoff, D; Pollara, J; Luo, K; Tolbert, WD; Young, B; Mielke, D; Jha, S; O'Connell, RJ; Vasan, S; Kim, J; Michael, NL; Excler, J-L; Robb, ML; Rerks-Ngarm, S; Kaewkungwal, J; Pitisuttithum, P; Nitayaphan, S; Sinangil, F; Tartaglia, J; Phogat, S; Kepler, TB; Alam, SM; Wiehe, K; Saunders, KO; Montefiori, DC; Tomaras, GD; Moody, MA; Pazgier, M; Haynes, BF; Ferrari, G
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation. (12/2019)
Saunders, KO; Wiehe, K; Tian, M; Acharya, P; Bradley, T; Alam, SM; Go, EP; Scearce, R; Sutherland, L; Henderson, R; Hsu, AL; Borgnia, MJ; Chen, H; Lu, X; Wu, NR; Watts, B; Jiang, C; Easterhoff, D; Cheng, H-L; McGovern, K; Waddicor, P; Chapdelaine-Williams, A; Eaton, A; Zhang, J; Rountree, W; Verkoczy, L; Tomai, M; Lewis, MG; Desaire, HR; Edwards, RJ; Cain, DW; Bonsignori, M; Montefiori, D; Alt, FW; Haynes, BF
Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies. (12/2019)
LaBranche, CC; Henderson, R; Hsu, A; Behrens, S; Chen, X; Zhou, T; Wiehe, K; Saunders, KO; Alam, SM; Bonsignori, M; Borgnia, MJ; Sattentau, QJ; Eaton, A; Greene, K; Gao, H; Liao, H-X; Williams, WB; Peacock, J; Tang, H; Perez, LG; Edwards, RJ; Kepler, TB; Korber, BT; Kwong, PD; Mascola, JR; Acharya, P; Haynes, BF; Montefiori, DC
Cooperation between somatic mutation and germline-encoded residues enables antibody recognition of HIV-1 envelope glycans. (12/2019)
Wu, NR; Nicely, NI; Lee, EM; Reed, RK; Watts, BE; Cai, F; Walkowicz, WE; Aussedat, B; Jones, JA; Eaton, A; Trama, AM; Alam, SM; Montefiori, DC; Haynes, BF; Saunders, KO
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies. (09/2019)
LaBranche, CC; Henderson, R; Hsu, A; Behrens, S; Chen, X; Zhou, T; Wiehe, K; Saunders, KO; Alam, SM; Bonsignori, M; Borgnia, MJ; Sattentau, QJ; Eaton, A; Greene, K; Gao, H; Liao, H-X; Williams, WB; Peacock, J; Tang, H; Perez, LG; Edwards, RJ; Kepler, TB; Korber, BT; Kwong, PD; Mascola, JR; Acharya, P; Haynes, BF; Montefiori, DC
Determinants of Tenascin-C and HIV-1 envelope binding and neutralization. (07/2019)
Mangan, RJ; Stamper, L; Ohashi, T; Eudailey, JA; Go, EP; Jaeger, FH; Itell, HL; Watts, BE; Fouda, GG; Erickson, HP; Alam, SM; Desaire, H; Permar, SR
Difficult-to-neutralize global HIV-1 isolates are neutralized by antibodies targeting open envelope conformations. (07/2019)
Han, Q; Jones, JA; Nicely, NI; Reed, RK; Shen, X; Mansouri, K; Louder, M; Trama, AM; Alam, SM; Edwards, RJ; Bonsignori, M; Tomaras, GD; Korber, B; Montefiori, DC; Mascola, JR; Seaman, MS; Haynes, BF; Saunders, KO

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