Publications Durham NC | HIV Publications & Articles

Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses

Kevin O Saunders Esther Lee, Robert Parks, David R Martinez, Dapeng Li , Haiyan Chen, Robert J Edwards, Sophie Gobeil, Maggie Barr, Katayoun Mansouri, S Munir Alam, Laura L Sutherland, Fangping Cai, Aja M Sanzone, Madison Berry, Kartik Manne, Kevin W Bock, Mahnaz Minai, Bianca M Nagata, Anyway B Kapingidza, Mihai Azoitei, Longping V Tse, Trevor D Scobey, Rachel L Spreng, R Wes Rountree, C Todd DeMarco, Thomas N Denny, Christopher W Woods, Elizabeth W Petzold, Juanjie Tang, Thomas H Oguin 3rd, Gregory D Sempowski, Matthew Gagne, Daniel C Douek, Mark A Tomai, Christopher B Fox, Robert Seder, Kevin Wiehe, Drew Weissman, Norbert Pardi, Hana Golding, Surender Khurana, Priyamvada Acharya, Hanne Andersen, Mark G Lewis, Ian N Moore, David C Montefiori, Ralph S Baric, Barton F Haynes. Nature. 2021 Jun;594(7864):553-559. doi: 10.1038/s41586-021-03594-0. Epub 2021 May 10.

Uterine NK cell education: Learning the ropes in pregnancy

Alexandra I Wells, Carolyn B Coyne. Immunity. 2021 Jun 8;54(6):1102-1104. doi: 10.1016/j.immuni.2021.05.009.

T cell-depleted cultured pediatric thymus tissue as a model for some aspects of human age-related thymus involution

Laura P Hale, Lynn Cheatham, Andrew N Macintyre, Bonnie LaFleur, Brittany Sanders, Jesse Troy, Joanne Kurtzberg, Gregory D Sempowski. Geroscience. 2021 Jun;43(3):1369-1382. doi: 10.1007/s11357-020-00301-1. Epub 2021 Jan 9.

Differential immune imprinting by influenza virus vaccination and infection in nonhuman primates

Kevin R McCarthy, Tarra A Von Holle, Laura L Sutherland, Thomas H Oguin 3rd, Gregory D Sempowski, Stephen C Harrison, M Anthony Moody. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2026752118. doi: 10.1073/pnas.2026752118.

Safety and immunogenicity of an HIV-1 gp120-CD4 chimeric subunit vaccine in a phase 1a randomized controlled trial

Joel V Chua, Charles Davis, Jennifer S Husson, Amy Nelson, Ilia Prado, Robin Flinko, Ka Wing J Lam, Lydiah Mutumbi, Bryan T Mayer, Dan Dong, William Fulp, Celia Mahoney, Monica Gerber, Raphael Gottardo, Bruce L Gillia, Kelli Greene, Hongmei Gao, Nicole Yates, Guido Ferrari, Georgia Tomaras, David Montefiori, Jennifer A Schwartz, Timothy Fouts, Anthony L DeVico, George K Lewis, Robert C Gallo, Mohammad M Sajadi. Vaccine. 2021 Jun 29;39(29):3879-3891. doi: 10.1016/j.vaccine.2021.05.090.

Four-parameter paired response curve for serial dilution assays

Youyi Fong, Sallie R Permar, Georgia D Tomaras. J Biopharm Stat. 2021 Jun 7;1-16. doi: 10.1080/10543406.2021.1931271. Online ahead of print.

Rectal and vaginal tissue from intravenous VRC01 recipients show protection against ex vivo HIV-1 challenge

Rena D Astronomo, Maria P Lemos, Sandeep R Narpala, Julie Czartoski, Lamar Ballweber Fleming, Kelly E Seaton, Madhu Prabhakaran, Yunda Huang, Yiwen Lu, Katharine Westerberg, Lily Zhang, Mary K Gross, John Hural, Hong-Van Tieu, Lindsey R Baden, Scott Hammer, Ian Frank, Christina Ochsenbauer, Nicole Grunenberg, Julie E Ledgerwood, Kenneth Mayer, Georgia Tomaras, Adrian B McDermott, M Juliana McElrath. J Clin Invest. 2021 Jun 24;146975. doi: 10.1172/JCI146975. Online ahead of print.

Structural and genetic convergence of HIV-1 neutralizing antibodies in vaccinated non-human primates

Fangping Cai, Wei-Hung Chen, Weimin Wu, Julia A Jones, Misook Choe, Neelakshi Gohain, Xiaoying Shen, Celia LaBranche, Amanda Eaton, Laura Sutherland, Esther M Lee, Giovanna E Hernandez, Nelson R Wu, Richard Scearce, Michael S Seaman, M Anthony Moody, Sampa Santra, Kevin Wiehe, Georgia D Tomaras, Kshitij Wagh, Bette Korber, Mattia Bonsignori, David C Montefiori, Barton F Haynes, Natalia de Val, M Gordon Joyce, Kevin O Saunders. PLoS Pathog. 2021 Jun 4;17(6):e1009624. doi: 10.1371/journal.ppat.1009624. eCollection 2021 Jun.

Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity

Sophie M-C Gobeil, Katarzyna Janowska, Shana McDowell, Katayoun Mansouri, Robert Parks, Victoria Stalls, Megan F Kopp, Kartik Manne, Dapeng Li, Kevin Wiehe, Kevin O Saunders, Robert J Edwards, Bette Korber, Barton F Haynes, Rory Henderson, Priyamvada Acharya. Science. 2021 Jun 24;eabi6226. doi: 10.1126/science.abi6226. Online ahead of print.

Cross-reactive coronavirus antibodies with diverse epitope specificities and Fc effector functions

Andrea R Shiakolas, Kevin J Kramer, Daniel Wrapp, Simone I Richardson, Alexandra Schäfer, Steven Wall, Nianshuang Wang, Katarzyna Janowska, Kelsey A Pilewski, Rohit Venkat, Robert Parks, Nelia P Manamela, Nagarajan Raju, Emilee Friedman Fechter, Clinton M Holt, Naveenchandra Suryadevara, Rita E Chen, David R Martinez, Rachel S Nargi, Rachel E Sutton, Julie E Ledgerwood, Barney S Graham, Michael S Diamond, Barton F Haynes, Priyamvada Acharya, Robert H Carnahan, James E Crowe Jr , Ralph S Baric, Lynn Morris, Jason S McLellan, Ivelin S Georgiev. Cell Rep Med. 2021 Jun 15;2(6):100313. doi: 10.1016/j.xcrm.2021.100313. Epub 2021 May 21.

Publications