John Franklin Whitesides, PhD


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Assistant Professor in Medicine
Department / Division:
Medicine / Medicine - DHVI Faculty
909 South Lasalle Street
Ghrb Room 1029
Durham, NC 27705
Office Telephone:
(919) 684-4895
  • PhD, Auburn University, 1990
Representative Publications:
  • Moody, MA; Yates, NL; Amos, JD; Drinker, MS; Eudailey, JA; Gurley, TC; Marshall, DJ; Whitesides, JF; Chen, X; Foulger, A; Yu, JS; Zhang, R; Meyerhoff, RR; Parks, R; Scull, JC; Wang, L; Vandergrift, NA; Pickeral, J; Pollara, J; Kelsoe, G; Alam, SM; Ferrari, G; Montefiori, DC; Voss, G; Liao, HX; Tomaras, GD; Haynes, BF. HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages. Journal of virology. 2012;86:7496-7507.  Abstract
  • Bonsignori, M; Hwang, KK; Chen, X; Tsao, CY; Morris, L; Gray, E; Marshall, DJ; Crump, JA; Kapiga, SH; Sam, NE; Sinangil, F; Pancera, M; Yongping, Y; Zhang, B; Zhu, J; Kwong, PD; O'Dell, S; Mascola, JR; Wu, L; Nabel, GJ; Phogat, S; Seaman, MS; Whitesides, JF; Moody, MA; Kelsoe, G; Yang, X; Sodroski, J; Shaw, GM; Montefiori, DC; Kepler, TB; Tomaras, GD; Alam, SM; Liao, HX; Haynes, BF. Analysis of a clonal lineage of HIV-1 envelope V2/V3 conformational epitope-specific broadly neutralizing antibodies and their inferred unmutated common ancestors. Journal of virology. 2011;85:9998-10009.  Abstract
  • Liao, HX; Chen, X; Munshaw, S; Zhang, R; Marshall, DJ; Vandergrift, N; Whitesides, JF; Lu, X; Yu, JS; Hwang, KK; Gao, F; Markowitz, M; Heath, SL; Bar, KJ; Goepfert, PA; Montefiori, DC; Shaw, GC; Alam, SM; Margolis, DM; Denny, TN; Boyd, SD; Marshal, E; Egholm, M; Simen, BB; Hanczaruk, B; Fire, AZ; Voss, G; Kelsoe, G; Tomaras, GD; Moody, MA; Kepler, TB; Haynes, BF. Initial antibodies binding to HIV-1 gp41 in acutely infected subjects are polyreactive and highly mutated. The Journal of Experimental Medicine. 2011;208:2237-2249.  Abstract
  • Lanasa, MC; Allgood, SD; Volkheimer, AD; Gockerman, JP; Whitesides, JF; Goodman, BK; Moore, JO; Weinberg, JB; Levesque, MC. Single-cell analysis reveals oligoclonality among 'low-count' monoclonal B-cell lymphocytosis. Leukemia. 2010;24:133-140.  Abstract
  • Lee, SM; Wyse, A; Lesher, A; Everett, ML; Lou, L; Holzknecht, ZE; Whitesides, JF; Spears, PA; Bowles, DE; Lin, SS; Tonkonogy, SL; Orndorff, PE; Bollinger, RR; Parker, W. Adaptation in a mouse colony monoassociated with Escherichia coli K-12 for more than 1,000 days. Applied and environmental microbiology. 2010;76:4655-4663.  Abstract
  • Gasper-Smith, N; Crossman, DM; Whitesides, JF; Mensali, N; Ottinger, JS; Plonk, SG; Moody, MA; Ferrari, G; Weinhold, KJ; Miller, SE; Reich, CF; Qin, L; Self, SG; Shaw, GM; Denny, TN; Jones, LE; Pisetsky, DS; Haynes, BF. Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design. Journal of virology. 2008;82:7700-7710.  Abstract