Publications - 2014

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  1. Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms.
    Goldberg EL, Romero-Aleshire MJ, Renkema KR, Ventevogel MS, Chew WM, Uhrlaub JL, Smithey MJ, Limesand KH, Sempowski GD, Brooks HL, Nikolich-Žugich J. Aging Cell. 2014 Nov 26. [Epub ahead of print]

  2. Infection of monkeys by simian-human immunodeficiency viruses with transmitted/founder clade C HIV-1 envelopes.
    Asmal M, Luedemann C, Lavine CL, Mach LV, Balachandran H, Brinkley C, Denny TN, Lewis MG, Anderson H, Pal R, Sok D, Le K, Pauthner M, Hahn BH, Shaw GM, Seaman MS, Letvin NL, Burton DR, Sodroski JG, Haynes BF, Santra S. Virology. 2014 Nov 22;475C:37-45.

  3. Impact of clade, geography, and age of the epidemic on HIV-1 neutralization by antibodies.
    Hraber P, Korber BT, Lapedes AS, Bailer RT, Seaman MS, Gao H, Greene KM, McCutchan F, Williamson C, Kim JH, Tovanabutra S, Hahn BH, Swanstrom R, Thomson MM, Gao F, Harris L, Giorgi E, Hengartner N, Bhattacharya T, Mascola JR, Montefiori DC. J Virol. 2014 Nov;88(21):12623-43.

  4. Preexisting compensatory amino acids compromise fitness costs of a HIV-1 T cell escape mutation.
    Liu D, Zuo T, Hora B, Song H, Kong W, Yu X, Goonetilleke N, Bhattacharya T, Perelson AS, Haynes BF, McMichael AJ, Gao F. Retrovirology. 2014 Nov 19;11(1):101. [Epub ahead of print]

  5. Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees.
    Moody MA, Easterhoff D, Gurley TC, Whitesides JF, Marshall DJ, Foulger A, Lloyd KE, Parks R, Pollara J, Duffy R, Shen S, Kim JH, Michael NL, Robb ML, O'Connell RJ, Vasan S, Excler JL, Rerks-Ngarm S, Kaewkungwal J, Pitisuttithum P, Nitayaphan S, Sinangil F, Francis D, Lee C, Kepler TB, Alam SM, Ferrari G, Montefiori DC, Liao HX, Tomaras GD, Haynes BF. AIDS Res Hum Retroviruses. 2014 Oct; 30(S1): A36. No abstract available.

  6. Role of Intestinal Microbiota in Shaping the B Cell Repertoire in HIV Infection and Env Vaccination.
    Liao LH, Trama AM, Williams WB, Moody MA, Vandergrift N, Tomaras GD, Marshall DJ, Gurley T, Whitesides J, Eudailey J, Foulger A, Parks R, Stolarchuk C, Lloyd KE, Soderberg K, Mascola JR, Koup R, Corey L, Nabel GB, Gilber P, Morgan C, Maenza J, Keefer M, Hammer S, Churchyard G, Montefior DC, Graham BS, Baden LR, Kepler TB, Haynes BF. AIDS Res Hum Retroviruses. 2014 Oct; 30(S1): A19. No abstract available.

  7. Polyreactivity and Autoreactivity among HIV-1 Antibodies.
    Liu M, Yang G, Wiehe K, Nicely NI, Vandergrift NA, Rountree W, Bonsignori M, Alam SM, Gao J,Haynes BF, Kelsoe G. J Virol. 2014 Oct 29. pii: JVI.02378-14. [Epub ahead of print]

  8. Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
    Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, Tumba N, Yang Y, Zhang B, Cohen MS, Haynes BF, Mascola JR, Morris L, Munro JB, Blanchard SC, Mothes W, Connors M, Kwong PD. Nature. 2014 Oct 8. doi: 10.1038/nature13808. [Epub ahead of print]

  9. Gene Deletions in BCG Stimulate Increased CD8+ T Cell Responses.
    Panas MW, Sixsmith JD, White K, Korioth-Schmitz B, Shields ST, Moy BT, Lee S, Schmitz JE, Jacobs WR Jr, Porcelli SA, Haynes BF, Letvin NL, Gillard GO. Infect Immun. 2014 Oct 6. pii: IAI.02100-14. [Epub ahead of print]

  10. Aggregate complexes of HIV-1 induced by multimeric antibodies.
    Stieh DJ, King DF, Klein K, Liu P, Shen X, Hwang K, Ferrari G, Montefiori DC, Haynes B, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Rerks-Ngarm S, Michael NL, Robb ML, Kim JH, Denny TN, Tomaras GD, Shattock RJ. Retrovirology. 2014 Oct 2;11(1):78. [Epub ahead of print]

  11. HIV-specific humoral responses benefit from stronger prime in phase Ib clinical trial.
    Bart PA, Huang Y, Karuna ST, Chappuis S, Gaillard J, Kochar N, Shen X, Allen MA, Ding S, Hural J, Liao HX, Haynes BF, Graham BS, Gilbert PB, McElrath MJ, Montefiori DC, Tomaras GD, Pantaleo G, Frahm N. J Clin Invest. 2014 Oct 1. pii: 75894. doi: 10.1172/JCI75894. [Epub ahead of print]

  12. Improving Mycobacterium bovis Bacillus Calmette-Guèrin as a Vaccine Delivery Vector for Viral Antigens by Incorporation of Glycolipid Activators of NKT Cells.
    Venkataswamy MM, Ng TW, Kharkwal SS, Carreño LJ, Johnson AJ, Kunnath-Velayudhan S, Liu Z, Bittman R, Jervis PJ, Cox LR, Besra GS, Wen X, Yuan W, Tsuji M, Li X, Ho DD, Chan J, Lee S, Frothingham R, Haynes BF, Panas MW, Gillard GO, Sixsmith JD, Korioth-Schmitz B, Schmitz JE, Larsen MH, Jacobs WR Jr, Porcelli SA. PLoS One. 2014 Sep 25;9(9):e108383. doi: 10.1371/journal.pone.0108383. eCollection 2014.

  13. Tolerance and immunity after sequential lung and bone marrow transplantation from an unrelated cadaveric donor.
    Szabolcs P, Buckley RH, Davis RD, Moffet J, Voynow J, Antony J, Chen X, Sempowski GD, Zaas DW. J Allergy Clin Immunol. 2014 Sep 24. pii: S0091-6749(14)01112-9. doi: 10.1016/j.jaci.2014.07.058. [Epub ahead of print] No abstract available.

  14. TLR2 Signaling is Required for the Innate, but Not Adaptive Response to LVS clpB.
    Roberts LM, Ledvina HE, Sempowski GD, Frelinger JA. Front Immunol. 2014 Sep 5;5:426. doi: 10.3389/fimmu.2014.00426. eCollection 2014.

  15. Extensive Recombination Due to Heteroduplexes Generates Large Amounts of Artificial Gene Fragments during PCR.
    Liu J, Song H, Liu D, Zuo T, Lu F, Zhuang H, Gao F. PLoS One. 2014 Sep 11;9(9):e106658. doi: 10.1371/journal.pone.0106658. eCollection 2014.

  16. Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses.
    Richard J, Veillette M, Batraville LA, Coutu M, Chapleau JP, Bonsignori M, Bernard N, Tremblay C, Roger M, Kaufmann DE, Finzi A. J Virol Methods. 2014 Aug 12;208C:107-114. doi: 10.1016/j.jviromet.2014.08.003. [Epub ahead of print]

  17. Immunoglobulin Gene Insertions and Deletions in the Affinity Maturation of HIV-1 Broadly Reactive Neutralizing Antibodies.
    Kepler TB, Liao HX, Alam SM, Bhaskarabhatla R, Zhang R, Yandava C, Stewart S, Anasti K, Kelsoe G, Parks R, Lloyd KE, Stolarchuk C, Pritchett J, Solomon E, Friberg E, Morris L, Karim SS, Cohen MS, Walter E, Moody MA, Wu X, Altae-Tran HR, Georgiev IS, Kwong PD, Boyd SD, Fire AZ, Mascola JR,Haynes BF. Cell Host Microbe. 2014 Sep 10;16(3):304-313. doi: 10.1016/j.chom.2014.08.006.

  18. Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
    Huang J, Kang BH, Pancera M, Lee JH, Tong T, Feng Y, Georgiev IS, Chuang GY, Druz A, Doria-Rose NA, Laub L, Sliepen K, van Gils MJ, de la Peña AT, Derking R, Klasse PJ, Migueles SA, Bailer RT, Alam M, Pugach P, Haynes BF, Wyatt RT, Sanders RW, Binley JM, Ward AB, Mascola JR, Kwong PD, Connors M. Nature. 2014 Sep 3. doi: 10.1038/nature13601. [Epub ahead of print]

  19. Potent immune responses in rhesus macaques induced by non-viral delivery of a self-amplifying RNA vaccine expressing HIV-1 envelope with a cationic nanoemulsion.
    Bogers WM, Oostermeijer H, Mooij P, Koopman G, Verschoor EJ, Davis D, Ulmer JB, Brito LA, Cu Y, Banerjee K, Otten GR, Burke B, Dey A, Heeney JL, Shen X, Tomaras GD, Labranche C, Montefiori DC, Liao HX, Haynes B, Geall AJ, Barnett SW. J Infect Dis. 2014 Sep 18. pii: jiu522. [Epub ahead of print]

  20. Editor's Choice: Infant HIV-1 gp120 vaccination elicits robust and durable anti-V1V2 IgG responses and only rare Envelope-specific IgA responses.
    Genevieve G. Fouda, Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, Brooke E. Liebl, Kaylan Whitaker, Xiaoying Shen, Nathan A. Vandergrift, R. Glenn Overman, Nicole L. Yates, M. Anthony Moody, Carrie Fry, Jerome H. Kim, Nelson L. Michael, Merlin Robb, Punnee Pitisuttithum, Jaranit Kaewkungwal, Sorachai Nitayaphan, Supachai Rerks-Ngarm, Hua-Xin Liao, Barton F. Haynes, David C. Montefiori, Guido Ferrari, Georgia D. Tomaras, and Sallie R. Permar. J Infect Dis. First published online August 27, 2014 doi:10.1093/infdis/jiu444

  21. Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo.
    Rudicell RS, Kwon YD, Ko SY, Pegu A, Louder MK, Georgiev IS, Wu X, Zhu J, Boyington JC, Chen X, Shi W, Yang ZY, Doria-Rose NA, McKee K, O'Dell S, Schmidt SD, Chuang GY, Druz A, Soto C, Yang Y, Zhang B, Zhou T, Todd JP, Lloyd KE, Eudailey J, Roberts KE, Donald BR, Bailer RT, Ledgerwood J; NISC Comparative Sequencing Program, Mullikin JC, Shapiro L, Koup RA, Graham BS, Nason MC, Connors M, Haynes BF, Rao SS, Roederer M, Kwong PD, Mascola JR, Nabel GJ. J Virol. 2014 Aug 20. pii: JVI.02213-14. [Epub ahead of print]

  22. IMPACT OF CLADE, GEOGRAPHY AND AGE OF THE EPIDEMIC ON HIV-1 NEUTRALIZATION BY ANTIBODIES.
    Hraber P, Korber BT, Lapedes AS, Bailer RT, Seaman MS, Gao H, Greene KM, McCutchan F, Williamson C, Kim JH, Tovanabutra S, Hahn BH, Swanstrom R, Thomson MM, Gao F, Harris L, Giorgi E, Hengartner N, Bhattacharya T, Mascola JR, Montefiori DC. J Virol. 2014 Aug 20. pii: JVI.01705-14. [Epub ahead of print]

  23. Flow cytometry-based assay to study HIV-1 gp120 specific antibody-dependent cellular cytotoxicity responses.
    Richard J, Veillette M, Batraville LA, Coutu M, Chapleau JP, Bonsignori M, Bernard N, Tremblay C, Roger M, Kaufmann DE, Finzi A. J Virol Methods. 2014 Aug 12. pii: S0166-0934(14)00310-3. doi: 10.1016/j.jviromet.2014.08.003. [Epub ahead of print]

  24. HIV-1 Envelope gp41 Antibodies Can Originate from Terminal Ileum B Cells that Share Cross-Reactivity with Commensal Bacteria.
    Trama AM, Moody MA, Alam SM, Jaeger FH, Lockwood B, Parks R, Lloyd KE, Stolarchuk C, Scearce R, Foulger A, Marshall DJ, Whitesides JF, Jeffries TL Jr, Wiehe K, Morris L, Lambson B, Soderberg K, Hwang KK, Tomaras GD, Vandergrift N, Jackson KJ, Roskin KM, Boyd SD, Kepler TB, Liao HX,Haynes BF. Cell Host Microbe. 2014 Aug 13;16(2):215-226. doi: 10.1016/j.chom.2014.07.003.

  25. Progress in HIV-1 vaccine development.
    Haynes BF, Moody MA, Alam M, Bonsignori M, Verkoczy L, Ferrari G, Gao F, Tomaras GD, Liao HX, Kelsoe G. J Allergy Clin Immunol. 2014 Jul;134(1):3-10. doi: 10.1016/j.jaci.2014.04.025. Epub 2014 Jun 26. Review.

  26. FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.
    Li SS, Gilbert PB, Tomaras GD, Kijak G, Ferrari G, Thomas R, Pyo CW, Zolla-Pazner S, Montefiori D, Liao HX, Nabel G, Pinter A, Evans DT, Gottardo R, Dai JY, Janes H, Morris D, Fong Y, Edlefsen PT, Li F, Frahm N, Alpert MD, Prentice H, Rerks-Ngarm S, Pitisuttithum P, Kaewkungwal J, Nitayaphan S, Robb ML, O'Connell RJ, Haynes BF, Michael NL, Kim JH, McElrath MJ, Geraghty DE. J Clin Invest. 2014 Aug 8. pii: 75539. doi: 10.1172/JCI75539. [Epub ahead of print]

  27. Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women.
    Sacha CR, Vandergrift N, Jeffries TL Jr, McGuire E, Fouda GG, Liebl B, Marshall DJ, Gurley TC, Stiegel L, Whitesides JF, Friedman J, Badiabo A, Foulger A, Yates NL, Tomaras GD, Kepler TB, Liao HX, Haynes BF, Moody MA, Permar SR.
    Mucosal Immunol. 2014 Aug 6. doi: 10.1038/mi.2014.69. [Epub ahead of print]

  28. Recombinant Bacillus Calmette-Guérin vectors prime for strong cellular responses to SIV Gag in rhesus macaques.
    Sixsmith JD, Panas MW, Lee S, Gillard GO, White K, Lifton MA, Balachandran H, Mach L, Miller JP, Lavine C, DeMarco CT, Tomaras GD, Gee C, Porcelli SA, Larsen MH, Frothingham R, Schmitz JE, Jacobs WR Jr, Haynes BF, Letvin NL, Korioth-Schmitz B. Clin Vaccine Immunol. 2014 Jul 30. pii: CVI.00324-14. [Epub ahead of print]

  29. Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies.
    Gao F, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, Kelsoe G, Shaw GM, Hahn BH, Montefiori DC, Kamanga G, Cohen MS, Hraber P, Kwong PD, Korber BT, Mascola JR, Kepler TB, Haynes BF. Cell. 2014 Jul 23. pii: S0092-8674(14)00812-5. doi: 10.1016/j.cell.2014.06.022. [Epub ahead of print]

  30. HIV-1 Specific IgA Detected in Vaginal Secretions of HIV Uninfected Women Participating in a Microbicide Trial in Southern Africa Are Primarily Directed Toward gp120 and gp140 Specificities.
    Seaton KE, Ballweber L, Lan A, Donathan M, Hughes S, Vojtech L, Moody MA, Liao HX, Haynes BF, Galloway CG, Richardson BA, Karim SA, Dezzutti CS, McElrath MJ, Tomaras GD, Hladik F. PLoS One. 2014 Jul 23; 9(7): e101863. doi: 10.1371/journal.pone.0101863. eCollection 2014.

  31. Reversion and T Cell Escape Mutations Compensate the Fitness Loss of a CD8+ T Cell Escape Mutant in Their Cognate Transmitted/Founder Virus.
    Song H, Hora B, Bhattacharya T, Goonetilleke N, Liu MK, Wiehe K, Li H, Iyer SS, McMichael AJ, Perelson AS, Gao F. PLoS One. 2014 Jul 16;9(7):e102734. doi: 10.1371/journal.pone.0102734. eCollection 2014.

  32. HIV-1 Antibodies and Vaccine Antigen Selectively Interact with Lipid Domains.
    Hardy GJ, Wong GC, Nayak R, Anasti K, Hirtz M, Shapter JG, Alam SM, Zauscher S. Biochim Biophys Acta. 2014 Jul 11. pii: S0005-2736(14)00251-X. doi: 10.1016/j.bbamem.2014.07.007. [Epub ahead of print]

  33. Will studies in individuals with systemic lupus erythematosus be the key to future HIV vaccine design?
    Bonsignori M. Expert Rev Vaccines. 2014 Jul 12:1-4. [Epub ahead of print]

  34. Envelope Glycoprotein Binding to the α4β7 Integrin Complex is not a General Property of Most HIV-1 Variants.
    Perez LG, Chen H, Liao HX, Montefiori DC. J Virol. 2014 Jul 9. pii: JVI.03296-13. [Epub ahead of print]

  35. Histone Deacetylation Critically Determines T Cell Subset Radiosensitivity.
    Pugh JL, Sukhina AS, Seed TM, Manley NR, Sempowski GD, van den Brink MR, Smithey MJ, Nikolich-Žugich J. J Immunol. 2014 Jul 2. pii: 1400434. [Epub ahead of print]

  36. Toward development of a comprehensive external quality assurance program for polyfunctional intracellular cytokine staining assays.
    Staats JS, Enzor JH, Sanchez AM, Rountree W, Chan C, Jaimes M, Chan RC, Gaur A, Denny TN, Weinhold KJ. J Immunol Methods. 2014 Jun 23. pii: S0022-1759(14)00186-0. doi: 10.1016/j.jim.2014.05.021. [Epub ahead of print] Review.

  37. Affinity maturation in an HIV broadly neutralizing B-cell lineage through reorientation of variable domains.
    Fera D, Schmidt AG, Haynes BF, Gao F, Liao HX, Kepler TB, Harrison SC. Proc Natl Acad Sci U S A. 2014 Jun 30. pii: 201409954. [Epub ahead of print]

  38. Human Responses to Influenza Vaccination Show Seroconversion Signatures and Convergent Antibody Rearrangements.
    Jackson KJ, Liu Y, Roskin KM, Glanville J, Hoh RA, Seo K, Marshall EL, Gurley TC, Moody MA,  Haynes BF, Walter EB, Liao HX, Albrecht RA, García-Sastre A, Chaparro-Riggers J, Rajpal A, Pons J, Simen BB, Hanczaruk B, Dekker CL, Laserson J, Koller D, Davis MM, Fire AZ, Boyd SD. Cell Host Microbe. 2014 Jun 25. pii: S1931-3128(14)00184-X. doi: 10.1016/j.chom.2014.05.013. [Epub ahead of print]

  39. Leukopak PBMC sample processing for preparing quality control material to support proficiency testing programs.
    Garcia A, Keinonen S, Sanchez AM, Ferrari G, Denny TN, Moody MA. J Immunol Methods. 2014 Jun 10. pii: S0022-1759(14)00181-1. [Epub ahead of print]

  40. The Variable Loop 3 in the Envelope Glycoprotein Is Critical for the Atypical Coreceptor Usage of an HIV-1 Strain.
    Xiang Y, Liu W, Chen Y, Zhang C, Su W, Zhang Y, Sun J, Gao F, Jiang C. PLoS One. 2014 Jun 4;9(6):e98058.

  41. The Human Antibody Response to the Surface of Mycobacterium tuberculosis.
    Perley CC, Frahm M, Click EM, Dobos KM, Ferrari G, Stout JE, Frothingham R. PLoS One. 2014 Jun 11;9(2):e98938. doi: 10.1371/journal.pone.0098938. eCollection 2014.

  42. Vaccine induced HIV-1 envelope gp120 Constant Region 1-specific Antibodies Expose a CD4-inducible Epitope and Block the Interaction of HIV-1 gp140 With Galactosylceramide.
    Dennison SM, Anasti KM, Jaeger FH, Stewart SM, Pollara J, Liu P, Kunz EL, Zhang R, Vandergrift N, Permar S, Ferrari G, Tomaras GD, Bonsignori M, Michael NL, Kim JH, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Rerks-Ngarm S, Liao HX, Haynes BF, Alam SM. J Virol. 2014 Jun 11. pii: JVI.01031-14. [Epub ahead of print]

  43. The Immunology Quality Assessment Proficiency Testing Program for CD3+4+ and CD3+8+Lymphocyte Subsets: A ten year review via longitudinal mixed effects modeling.
    Bainbridge J, Wilkening CL, Rountree W, Louzao R, Wong J, Perza N, Garcia A, Denny TN. J Immunol Methods. 2014 Jun 6. pii: S0022-1759(14)00179-3. doi: 10.1016/j.jim.2014.05.017. [Epub ahead of print] Review.

  44. The Center for HIV/AIDS Vaccine Immunology (CHAVI) Multi-site Quality Assurance Program for Cryopreserved Human Peripheral Blood Mononuclear Cells.
    Sarzotti-Kelsoe M, Needham LK, Rountree W, Bainbridge J, Gray CM, Fiscus SA, Ferrari G, Stevens WS, Stager SL, Binz W, Louzao R, Long KO, Mokgotho P, Moodley N, Mackay M, Kerkau M, McMillion T, Kirchherr J, Soderberg KA, Haynes BF, Denny TN. J Immunol Methods. 2014 Jun 5. pii: S0022-1759(14)00175-6. doi: 10.1016/j.jim.2014.05.013. [Epub ahead of print]

  45. Redemption of autoreactive B cells.
    Haynes BF, Verkoczy L, Kelsoe G. Proc Natl Acad Sci U S A. 2014 Jun 11. pii: 201407877. [Epub ahead of print] No abstract available.

  46. Introduction for JIM Special Issue: Building Global Resource Programs to Support HIV/AIDS Clinical Trial Studies.
    Sanchez AM, Denny TN, O'Gorman M. J Immunol Methods. 2014 Jun 5. pii: S0022-1759(14)00178-1. doi: 10.1016/j.jim.2014.05.016. [Epub ahead of print] No abstract available.

  47. Transcriptional and Post-transcriptional Regulation of Cytokine Gene Expression in HIV-1 Antigen-specific CD8+ T Cells that Mediate Virus Inhibition.
    Payne TL, Blackinton J, Frisbee A, Pickeral J, Sawant S, Vandergrift NA, Freel SA, Ferrari G, Keene JD, Tomaras GD. J Virol. 2014 Jun 4. pii: JVI.00802-14. [Epub ahead of print]

  48. Which comes first: the antigen or the adjuvant?
    Permar SR, Staats HF. J Clin Invest. 2014 Jun 2;124(6):2364-5. doi: 10.1172/JCI76263. Epub 2014 May 16.

  49. Dusp3 and Psme3 Are Associated with Murine Susceptibility to Staphylococcus aureus Infection and Human Sepsis.
    Yan Q, Sharma-Kuinkel BK, Deshmukh H, Tsalik EL, Cyr DD, Lucas J, Woods CW, Scott WK,Sempowski GD, Thaden J, Rude TH, Ahn SH, Fowler VG Jr. PLoS Pathog. 2014 Jun 5;10(6):e1004149. doi: 10.1371/journal.ppat.1004149. eCollection 2014 Jun.

  50. The Haemophilus ducreyi trimeric autotransporter adhesin DsrA protects against an experimental infection in the swine model of chancroid.
    Fusco WG, Choudhary NR, Routh PA, Ventevogel MS, Smith VA, Koch GG, Almond GW, Orndorff PE, Sempowski GD, Leduc I. Vaccine. 2014 May 17. pii: S0264-410X(14)00698-7. doi: 10.1016/j.vaccine.2014.05.031. [Epub ahead of print]

  51. IFN-γ, but not IL-17A, is required for survival during secondary pulmonary Francisella tularensis Live Vaccine Stain infection.
    Roberts LM, Davies JS, Sempowski GD, Frelinger JA. Vaccine. 2014 May 14. pii: S0264-410X(14)00669-0. doi: 10.1016/j.vaccine.2014.05.013. [Epub ahead of print]

  52. Cross-reactive potential of human T-lymphocyte responses in HIV-1 infection.
    Giorgi EE, Balachandran H, Muldoon M, Letvin NL, Haynes BF, Korber BT, Santra S. Vaccine. 2014 May 13. pii: S0264-410X(14)00578-7. doi: 10.1016/j.vaccine.2014.04.040. [Epub ahead of print]

  53. HIV-1 envelope gp41 broadly neutralizing antibodies: hurdles for vaccine development.
    Verkoczy L, Kelsoe G, Haynes BF. PLoS Pathog. 2014 May 22;10(5):e1004073. doi: 10.1371/journal.ppat.1004073. eCollection 2014 May. No abstract available.

  54. AIDS/HIV. Host controls of HIV neutralizing antibodies.
    Haynes BF, Verkoczy L. Science. 2014 May 9;344(6184):588-9. doi: 10.1126/science.1254990. Summary l Reprint l Full Text

  55. HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities.
    Pollara J, Bonsignori M, Moody MA, Liu P, Alam SM, Hwang KK, Gurley TC, Kozink DM, Armand LC, Marshall DJ, Whitesides JF, Kaewkungwal J, Nitayaphan S, Pitisuttithum P, Rerks-Ngarm S, Robb ML, O'Connell RJ, Kim JH, Michael NL, Montefiori DC, Tomaras GD, Liao HX, Haynes BF, Ferrari G. J Virol. 2014 May 7. [Epub ahead of print]

  56. Development and implementation of a proficiency testing program for Luminex bead-based cytokine assays.
    Lynch HE, Sanchez AM, D'Souza MP, Rountree W, Denny TN, Kalos M, Sempowski GD. J Immunol Methods. 2014 May 4. pii: S0022-1759(14)00128-8. doi: 10.1016/j.jim.2014.04.011. [Epub ahead of print] Review.

  57. Analysis of HLAA*02 association with vaccine efficacy in the RV144 HIV-1 vaccine trial.
    Gartland AJ, Li S, McNevin J, Tomaras GD, Gottardo R, Janes H, Fong Y, Morris D, Geraghty DE, Kijak GH, Edlefsen PT, Frahm N, Larsen BB, Tovanabutra S, Sanders-Buell E, deCamp AC, Magaret CA, Ahmed H, Goodridge JP, Chen L, Konopa P, Nariya S, Stoddard JN, Wong K, Zhao H, Deng W, Maust BS, Bose M, Howell S, Bates A, Lazzaro M, O'Sullivan A, Lei E, Bradfield A, Ibitamuno G, Assawadarachai V, O'Connell RJ, deSouza MS, Nitayaphan S, Rerks-Ngarm S, Robb ML, Sidney J, Sette A, Zolla-Pazner S, Montefiori D, McElrath MJ, Mullins JI, Kim JH, Gilbert PB, Hertz T. J Virol. 2014 May 14. pii: JVI.01164-14. [Epub ahead of print]

  58. Reconstructing a B-Cell Clonal Lineage. II. Mutation, Selection, and Affinity Maturation.
    Kepler TB, Munshaw S, Wiehe K, Zhang R, Yu JS, Woods CW, Denny TN, Tomaras GD, Alam SM, Moody MA, Kelsoe G, Liao HX, Haynes BF. Front Immunol. 2014 Apr 22;5:170. doi: 10.3389/fimmu.2014.00170. eCollection 2014.

  59. Osuna CE, Gonzalez AM, Chang HH, Hung AS, Ehlinger E, Anasti K, Alam SM, Letvin NL. TCR Affinity Associated with Functional Differences between Dominant and Subdominant SIV Epitope-Specific CD8+ T Cells in Mamu-A*01+ Rhesus Monkeys. PLoS Pathog. 2014 Apr 17;10(4):e1004069. doi: 10.1371/journal.ppat.1004069. eCollection 2014 Apr.

  60. Nair SK, Tomaras GD, Sales AP, Boczkowski D, Chan C, Plonk K, Cai Y, Dannull J, Kepler TB, Pruitt SK, Weinhold KJ. High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes. Sci Rep. 2014 Apr 23;4:4632.

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  76. Hwang KK, Trama AM, Kozink DM, Chen X, Wiehe K, Cooper AJ, Xia SM, Wang M, Marshall DJ, Whitesides J, Alam M, Tomaras GD, Allen SL, Rai KR, McKeating J, Catera R, Yan XJ, Chu CC, Kelsoe G, Liao HX, Chiorazzi N, Haynes BF. IGHV1-69 B Cell Chronic Lymphocytic Leukemia Antibodies Cross-React with HIV-1 and Hepatitis C Virus Antigens as Well as Intestinal Commensal Bacteria. PLoS One. 2014 Mar 10; 9(3): e90725.

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